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I work as an ornithologist - I study birds and their habitat. Africe is the best place on Earth to study these graceful creatures as nowhere else you will see such a diversity and brightfulness of birds. Every year I go to Africa and nearby islands at least twice and every time I have to think about my health before I go. Usually I take Chloroquine and it helps me keep away from malaria which is very common in Africa. I never experienced any of the side effects from similar medications that people claim about. I think I owe to this drug for still being able to do my beloved job and stay healthy and happy.
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I work as an international journalist and I travel a lot to countries with exotic nature. Every time when I am about to direct my steps to regions with malaria I take a course of Chloroquine. It helps me keep away from the disease and come back healthy. These medications can not be taken on a regular basis because of being very strong. So don't forget to consult with your doctor if you plan a trip to contaminated area. Malaria is a horrible disease and if you can prevent it don't hesitate. People talk about awful side effects after taking medications from malaria, but what I think is that vomiting and sweating is better than death anyway. The only side effect I experienced after starting on Chloroquine was mild fatigue. It soon disappeared though. So, think twice and then act!

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Moreover, the finding that single mutations to the protein can result in gross changes to parasite morphology emphasizes the central role of this transporter in the physiological processes that occur within the FV and provides a novel insight into one of the factors constraining the evolution of PfCRT.

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ABSTRACT CONCLUSIONS: Mefloquine was found to disrupt neuronal calcium homeostasis and induce an ER stress response at physiologically relevant concentrations, effects that may contribute, at least in part, to the neurotoxicity of the drug in vitro.

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When chloroquine is used for prophylaxis it is important to start the medication 1-2 weeks before travelling to the malaria affected areas and continue it till 4 week after leaving the malaria endemic areas.

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Michaelides M, Stover NB, Francis PJ, Weleber RG: Retinal toxicity associated with hydroxychloroquine and chloroquine: risk factors, screening, and progression despite cessation of therapy.

Real-time polymerase chain reaction assay for the rapid detection and characterization of chloroquine-resistant Plasmodium falciparum malaria in returned travelers.

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The effectiveness of chloroquine against the parasite has declined as some resistant forms of the parasite can effectively neutralize the drug by developing a mechanism that drains chloroquine away from the key area, preventing heme from reaching the necessary concentration.

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Treatment of tumor-bearing mice demonstrated that chloroquine could enhance ABT-737-mediated tumor growth inhibition against NCI-H209 xenografts, but did not alter ABT-737 response in three primary patient-derived xenograft models.

We demonstrated that chloroquine-resistant parasites in Malawi had haplotypes that were nearly identical to that of a chloroquine-resistant isolate from Southeast Asia at microsatellite loci flanking pfcrt.

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En el menú "Herramientas > Preferencias", dirígete a la pestaña "Seguridad".
En el menú "Aceptar cookies" seleccionar la casilla "Siempre" o "Nunca".