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Maternal methyl supplements increase offspring DNA methylation at Axin Fused.

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Cost-effectiveness of several atypical antipsychotics in orally disintegrating tablets compared with standard oral tablets in the treatment of schizophrenia in the United States.

In a previous study we showed abnormal cortico-cerebellar functional connectivity during execution of motor task only in schizophrenia patients (SZP) with sequencing deficit.

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Psychiatrists accept that Bipolar I Disorder requires indefinite treatment; yet many still don't accept that Schizophrenia requires indefinite treatment.

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Switching to Ziprasidone in the Clinical Practice Setting: An Open-Label Study.

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H1 receptors may explain the somnolence observed with this drug.

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ERG would be a valuable tool to investigate psychiatric disorder as the procedure is non-invasive, reproducible, very well tolerated by patients, healthy controls and children with no negative clinical reactions.

Further, given findings that oxytocin (OXT) may be associated with individual differences in affiliation, we sought to determine if lower plasma levels of OXT contribute to negative symptom severity and less positive subjective responding within an affiliative interaction.

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In vitro functional dopamine receptor antagonism by ziprasidone has been demonstrated by concentration-dependent blockade of effects induced by a D 2 agonist, quinpirole (inhibition of forskolin-stimulated adenylate cyclase) ().

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In order to disentangle mu-rhythm from alpha rhythm, the principal component analysis (PCA) was applied taking into the account the following specifications: mapping of mu-rhythm in sensorimotor cortex, the absence of the reaction on eyes opening, suppression of mu-rhythm during motion imagery task.

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We systematically reviewed the literature with the following goals: 1) to elucidate how resilience has been discussed in patients with schizophrenia, 2) to clarify the methods used to assess resilience, 3) and to review candidate biological mechanisms of resilience in schizophrenia.

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The information on this page has been compiled for use by healthcare practitioners and consumers in the United States and therefore neither Everyday Health or its licensor warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.

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Background: Research on the environmental risk factors for schizophrenia has focused on either psychosocial stress or drug exposure, with limited investigation of their interaction.

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Plasma accumulation of metabolism of orally administered single dose L-5-hydroxytryptophan in man".

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Results: Although there were significant effects of Risk Group, and Time effects, we observed no significant Time x Group effect.

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Methods: A spatial delayed response task was given to PSZ, REL, and healthy controls (HCs).

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Do not stop any medication or change the dose without first talking to your provider.

Multiple fixed doses of “Seroquel” (quetiapine) in patients with acute exacerbation of schizophrenia: a comparison with haloperidol and placebo.

Chronic treatment with olanzapine increases adiposity by changing fuel substrate and causes desensitization of the acute metabolic side effects.

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This subgroup of patients, characterized as it is by both brain loss and cognitive underperformance, may be both clinically and genetically distinct with implications for diagnosis, treatment and drug development in schizophrenia.

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Molecular pathophysiology of metabolic effects of antipsychotic medications.

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Relapse and therapeutic interventions in a 1-year observational cohort study of nonadherent outpatients with schizophrenia.

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Quetiapine is indicated for the treatment of schizophrenia and as either monotherapy or adjunctive therapy for acute manic episodes or as maintenance therapy in bipolar I disorder.

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The combination of memantine and galantamine has potential in reversing cognitive impairment in schizophrenia in conditions of chronic schizophrenia; however clinical trials need to proceed cautiously as smoking conditions and genotypes might affect the outcome.

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Ziprasidone is less likely to cause weight gain than other atypical antipsychotics and has not been linked to cases of steatosis.

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Appetite for energy-dense, high-carbohydrate foods showed the greatest increase ().

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Steve Williamson, consultant cancer pharmacist at Northumbria Healthcare NHS Foundation Trust, says the paper is important as a reality check to the continuing pressure to fund all new innovations in oncology that gain FDA and EMA approval.

Food and Drug Administration (FDA) is warning that the antipsychotic medicine olanzapine can cause a rare but serious skin reaction that can progress to affect other parts of the body.

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Voxelwise t-tests for group and medication comparisons were performed using AFNI.

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Background: Evidence indicates that social cognitive processes may be less related to measures of cold cognition and more related to processes such as reward sensitivity and reinforcement learning (RL).

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Background: Galantamine is an acetylcholinesterase inhibitor with allosteric potentiating effects on nicotinic receptors (nAChR) and memantine is a weak NMDA-antagonist with preferential affinity against the excitatory-inhibitory synapses in cortical networks.

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Neuroimaging as a potential biomarker to optimize psychiatric research and treatment.

Proximal effectiveness was examined as change in functional ability (as assessed using the UC-San Diego Performance-Based Skills Assessment), while distal effectiveness was rated as the change in real-world behavior (measured using the Specific Levels of Functioning Scale).

Campochiaro PA, Lim JI. Aminoglycoside toxicity in the treatment of endophthalmitis. Arch Ophthalmol.

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They are also sometimes prescribed for blood disorders, depression, schizophrenia, impulse control disorders, certain mental illnesses in children and schizoaffective disorder, a condition that is a combination of schizophrenia and mood disorder.

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Other adverse effects seen in trials of bipolar patients included extrapyramidal symptoms, dizziness, akathisia, and abnormal vision.

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Electroconvulsive therapy should not be prescribed as first line treatment or monotherapy in schizophrenia.

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Background: Negative symptoms are consistently related to a worse functional outcome and represent an unmet therapeutic need in people with psychosis.

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Using ICT to deliver psychoeducational interventions has no clear effects compared with standard care, other methods of delivering psychoeducation and support, or both.

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