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Several diagnostic strategies using ultrasound imaging, measurement of D-dimer, and assessment of clinical probability of disease have proved safe in patients with suspected deep-vein thrombosis, but they have not been compared in randomized trials.

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Participants Non-pregnant Danish women aged 15-49 with no history of thrombotic disease and followed from January 2001 to December 2009.

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Attitudes of Women Who are Currently Using or Recently Stopped Estrogen Replacement Therapy with or without Progestins: Results of the Aware Survey.

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Evidence is lacking regarding progestogen IUD usage for in bicornuate uterus, but a case report showed good effect with a single IUD for this purpose.

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The follow-up period was also relatively short (maximum of two years and three months), which limits the bias associated with changing diagnostic procedures and health system management of the three events of interest, and eliminated the potential time trend bias.

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Selecting a control group of women who had undergone biopsies but were not found to have EH would not be an acceptable alternative as they would not be expected to have hormone medication histories that would be representative of the general population from whence the cases arose.

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